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Herbs & Cultures
Image of Mayapple

North America · Herb · № 826

Podophyllum peltatum

Origin
Eastern North America
3 traditionsImage: Jennifer Anderson, USDA · Public domain

Herb · North America

Mayapple

Podophyllum peltatum

A poisonous plant whose resin, podophyllin, was once used as a laxative. Now only used in the form of medicines against warts.

Safety notes

All parts except the ripe fruit are poisonous. Do not use.

Cautions by tradition (3)
  • Healing traditions of the Americas: Poisonous; the resin causes serious poisoning if ingested.
  • Haudenosaunee (Iroquois) medicine: Root, leaves and unripe fruit are poisonous.
  • Cherokee (Tsalagi) medicine: Highly poisonous; do not take it.

Preparation

Do not prepare it yourself.

Use in traditions

Indigenous peoples and later the Eclectic physicians used the root. Modern medicines are derived from podophyllin.

Applications

Use by tradition

How different herbal traditions describe this herb. Amounts are traditional guidelines checked for obvious errors; they are not medical advice. For poisonous plants no dosage is given on purpose.

Healing traditions of the Americas

Attributed effects

Indigenous peoples used the root as a powerful laxative and vermifuge; Eclectic physicians adopted it. Modern remedies against warts and cancer have been derived from podophyllin.

Preparation and amount

Do not prepare or use it yourself.

Caution: Poisonous; the resin causes serious poisoning if ingested.